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Ggt1-cre

WebNov 27, 2024 · In Ggt1-Cre mice, Cre recombinase is expressed in RTECs 7–10 days after birth, and as a result Cre-mediated gene ablation is unlikely to influence normal renal development (32). Vgf PT−/− mice were indistinguishable from WT littermates and normal renal function was not evidently influenced by Vgf deficiency in RTECs ( Fig. S3 ). WebApr 5, 2014 · 目前已有的PEPCK-cre工具鼠仅有Hprttm1(Pck1-cre)Vhh变型启动子使肝中cre表达降低60%,而肝中cre表达提高10倍。 同时需注意此工具鼠中同时敲除了Hprt基 …

Acute Kidney Injury Instigates Malignant Renal Cell …

WebGgt1 Cre Transgenic Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - … WebThe genotyping protocol (s) presented here have been optimized for reagents and conditions used by The Jackson Laboratory (JAX). To genotype animals, JAX recommends researchers validate the assay independently upon receipt of animals into their facility. Reaction cycling temperature and times may require additional optimization based on the ... health plus dental https://group4materials.com

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WebFigure Legend Snippet: ( A ) Targeting construct was designed for integration into the ROSA26 region, and the expression cassette was designed with the CAG promoter-floxed stop codon-Trip13 cDNA-T2A-EGFP-polyA. 2A, protease cleavage site ( Trip13 cDNA was FLAG tagged at the 3′ end); CAG, CMV-IE enhancer/chicken β-actin/rabbit β-globin. ( B ) … WebFeb 5, 2012 · Here we show that the BMP receptor activin-like kinase 3 (Alk3) is elevated early in diseased kidneys after injury. We also found that its deletion in the tubular epithelium leads to enhanced TGF-β1-Smad family member 3 (Smad3) signaling, epithelial damage and fibrosis, suggesting a protective role for Alk3-mediated signaling in the kidney. WebSep 17, 2024 · Selective deletion of Arg2 in endothelial cells (Tie2 Cre /Arg2 fl/fl) reduced the level of fibrosis after UUO. In contrast, selective deletion of Arg2 specifically in … health plus diagnostic centre delhi

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Category:POS-064 DcR2 mediates the maladaptive repair of acute

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Ggt1-cre

Tg(Ggt1-cre/ERT2)1Pepe Transgene Detail MGI Mouse …

WebOct 12, 2024 · floxed mice (stock no. 013106, Jackson Laboratory) with Ggt1-Cre mice (stock no. 012841, Jackson Laboratory). We obtained mT/mG mice that express the cell membrane-targeted (mT), two-color fluores-cent Cre reporter allele from Jackson Laboratories (stock no. 007676). mT/mG mice were bred with the Ggt1-Cre strain to … WebNov 9, 2024 · Ggt1-Cre mice were crossed with Sox9-floxed mice to generate RTEC-specific knockout mice. Eight- to ten-wk-old male littermate control and cyclin-dependent kinase-like 5 (Cdkl5) conditional knockout male mice (indicated by Cdkl5 PT−/y ) were challenged with rhabdomyolysis (Rhabdo; 7.5 mL/kg of 50% glycerol in both hindleg …

Ggt1-cre

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http://www.informatics.jax.org/allele/MGI:3798834 WebAir Intake Screen - Big Rig World carries Genuine OEM and Aftermarket parts to repair your vehicle at the lowest prices. Brand: TRP TRPPC Unit of Measure: Each VMRS Code: …

WebApr 27, 2024 · Renal fibrosis in wild type and PT-Sirt6KO (Sirt6 flox/flox; Ggt1-Cre +) mice was induced by UUO surgery. After seven days, histologic examination and Western blot analysis were performed to examine extracellular matrix (ECM) protein expression. We evaluated inflammatory cytokine and cell adhesion molecule expression after ureteral … WebMar 7, 2024 · Mutation details: The rat proximal promoter to Ggt1 was used in a transgene construct to drive the expression of cre recombinase, followed by a termination …

WebFeb 1, 2024 · Additionally, quantitative proteomics and validated studies showed HMGCS2, a key enzyme for ketone synthesis, was increased in GGT1-cre DcR2 f/f mice compared … WebSep 1, 2004 · GGT-Cre mice for tissue-specific gene ablation in proximal kidney tubules. September 2004. DOI: 10.1240/sav_gbm_2004_h_000669.

WebIn this study, we crossed Trp53 and Pten conditional knockout mice with Ggt1-Cre mice to generate a Ggt1-Cre; Trp53 LoxP/LoxP; Pten LoxP/LoxP; YFP LoxP/LoxP (GPPY) …

WebMay 15, 2024 · In this study, we crossed Trp53 and Pten conditional knockout mice with Ggt1-Cre mice to generate a Ggt1-Cre; Trp53 LoxP/LoxP; Pten LoxP/LoxP; YFP … good dither fishWebDec 28, 2005 · 1101 Highway 171, Graceville, FL 32440 is a 1,120 sqft, 3 bed, 1 bath home sold in 2015. See the estimate, review home details, and search for homes nearby. health plus diagnostic clinic incWebMar 1, 2024 · wcn23-0488 decoy receptor 2 mediates tubular maladaptive repair by regulating ketogenesis after acute kidney injury healthplus dubaiWebTo breed corin kcKO mice, Cor flox mice were bred with Ggt1-Cre mice (Tg(Ggt1-cre)M3Egn/J, Jackson Laboratory, Bar Harbor, ME, USA), expressing renal Cre under the Ggt1 promoter [84,85] . The mice were crossed (>10 generations) into the C57BL/6J background. WT C57BL/6J mice were used as controls. health plus distributorsWebFeb 6, 2024 · Homozygous CrATloxP female mice (C57BL/6J) were bred to male γ-glutamyl transferase Cre mice (Tg-(Ggt1-cre)M3Egn/J, mixed Balb/cJ/C57BL/6 background; The … health plus doctorsWebMar 13, 2024 · The Ggt1-Cre mice have a mix of BALB/cJ and C57BL/6 background. Animal models of acute kidney injury Given that AKI is associated with distinct disease conditions, multiple mouse models have been developed. 20 Ischemia, cisplatin, and rhabdomyolysis-associated AKI was triggered in male mice aged 8–12 weeks using … good distro for video editingWebMay 18, 2015 · Inbred male DBA/2 mice were from Taconic. We have previously described the generation of the Ggt1-Cre transgenic mouse line ; this Ggt1-Cre mouse line was … gooddiveshop