Phosphinothricin tripeptide

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August undefined, 2024

WebJan 1, 2005 · The nonproteinogenic amino acid phosphinothricin is a structural glutamate analogue and potent inhibitor of glutamine synthetase, an enzyme central to nitrogen regulation in some plant cell types, making it an effective and widely used herbicide ( 4, 26 ). WebApr 23, 2010 · Indeed, known naturally occurring phosphonates such as K-26, phosphinothricin tripeptide (PTT), and fosfomycin ( Seto and Kuzuyama, 1999) are structurally diverse and affect diverse biological processes. Despite widespread use in medicine and agriculture, understanding the biosynthesis of these compounds is still in a …

N-Acetylphosphinothricin tripeptide C13H22N3O7P-2

WebJan 23, 1998 · Phosphinothricyl-alanyl-alanine (Pt tripeptide (Ptt), bialaphos) is a metabolite produced by Streptomyces viridochromogenes and Streptomyces hygroscopicus. It contains the unique phosphinoamino acid phosphinothricin (Pt), which after cleavage … WebN-Acetylphosphinothricin tripeptide C13H22N3O7P-2 CID 90657809 - structure, chemical names, physical and chemical properties, classification, patents, literature ... philippe thibodot

Biosynthetic gene cluster of the herbicide phosphinothricin tripeptide …

WebOct 1, 1996 · The bar and pat genes, isolated from different Streptomyces species, both encode a phosphinothricin acetyltransferase (PAT) and are widely applied in plant genetic engineering. The genes were... WebThe tripeptide backbone of phosphinothricin (PT) tripeptide (PTT), a compound with herbicidal activity from Streptomyces viridochromogenes, is assembled by three stand … WebGlufosinate (2-Amino-4-[hydroxy(methylphosphonoyl)] butanoic acid) was discovered by German and Japanese scientists in a biological process: Species of Streptomyces bacteria produce a tripeptide that consists of two alanine residues and an amino acid that is an analogue of glutamate named phosphinothricin. philippe thibault-denis conjointe

Phosphinothricin tripeptide synthetases in Streptomyces

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WebSubsequent tissue culture and regeneration steps allow recovery of plantlets, assisted by the inclusion of PPT (phosphinothricin tripeptide), the active ingredient of glufosinate-ammonium containing herbicides, to help select transformants. This updated method introduces selection earlier in the regeneration process which provides a shortened ... WebN-Acetyldemethylphosphinothricin tripeptide C12H21N3O7P+ CID 46174007 - structure, chemical names, physical and chemical properties, classification, patents ... trulia yellow pine idahoWebSummary: L-phosphinothricin is a non-proteinogenic amino acid that is a structural analogue of L-glutamate.As such, it is a potent inhibitor of glutamine synthetase, an enzyme central to nitrogen regulation in many bacterial and plant species [Bayer72, Lea84].It is the active ingredient in several nonselective systemic herbicides, including Basta, Rely, Finale, … trulia yamhill county

"WebJun 11, 2009 · One such compound, phosphinothricin tripeptide, contains the unusual amino acid phosphinothricin attached to two alanine residues. Synthetic phosphinothricin (glufosinate) is a component of... " - Phosphinothricin tripeptide

Phosphinothricin tripeptide

WebDOI: 10.7164/ANTIBIOTICS.37.939 Corpus ID: 9186238; The structure of phosalacine, a new herbicidal antibiotic containing phosphinothricin. @article{mura1984TheSO, title={The structure of phosalacine, a new herbicidal antibiotic containing phosphinothricin.}, author={Satoshi Ōmura and Kiyoizumi Hinotozawa and Nobutaka Imamura and Mitsuo … WebBialaphos is also known as phosphinothricin tripeptide, PTT. Phosphinothricin is not an effective antibiotic because of its inability to be readily transported across the cell …

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WebPhosphinothricin is produced by Streptomyces hygroscopicus ATCC 21705 and Streptomyces viridochromogenes DSM as a tripeptide, with its carboxylate bonded to an … WebPhosphonates or phosphonic acids are organic compounds containing C–PO (OH)2 or C–PO (OR) 2 groups (where R = alkyl, aryl). Most phosphonates are highly water soluble, while the phosphonic acids are only sparingly soluble. Phosphonates are not volatile and are poorly soluble in organic solvents.

WebDec 1, 2005 · Abstract and Figures. The tripeptide backbone of phosphinothricin (PT) tripeptide (PTT), a compound with herbicidal activity from Streptomyces viridochromogenes, is assembled by three stand-alone ... WebPhosphinothricin C5H11NO4P- CID 25244585 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ...

WebStreptomyces viridochromogenes Tü494 produces the antibiotic phosphinothricyl-alanyl-alanine (Ptt). Ptt-non-producing mutants were isolated following N-methyl-N′-nitro-N-nitrosoguanidine (NTG) or UV light treatment of spore suspensions. In co-synthesis and bioconversion experiments the mutational blocks in the biosynthetic pathway were … WebDec 1, 2005 · The tripeptide backbone of phosphinothricin (PT) tripeptide (PTT), a compound with herbicidal activity from Streptomyces viridochromogenes , is assembled …

WebPhsA is the initiation module for synthesis of the tripeptide (7) and contains an adenylation (A) domain that activates its substrate amino acid to the corresponding aminoacyl …

WebPhsA is the initiation module for synthesis of the tripeptide (7) and contains an adenylation (A) domain that activates its substrate amino acid to the corresponding aminoacyl adenylate, a... trulia yonkers ny rentalsWebCleaning compositions having engineered fatty acid alpha-dioxygenases and methods of using said compositions to provide a benefit by converting long chain fatty acids present in soils into 2-hydroperoxy fatty acids or terminal aldehydes. trulia yorktown vaWebSep 27, 2010 · Recent studies have started to reveal nature’s biosynthetic strategies toward several of these compounds, including the clinically used antibiotic fosfomycin (2–4), the antimalaria clinical candidate FR900098 (5, 6), the antifungal tripeptide rhizocticin , and the widely used herbicide phosphinothricin (8–12) (Fig. 1A). philippe thiels siiWebDec 1, 2004 · The discovery of a new peptide antibiotic was reported for Streptomyces viridochromogenes in 1972 and for Streptomyces hygroscopicus in 1973 ().The antibiotic, named phosphinothricin tripeptide (PTT) or bialaphos, consists of two molecules of l-alanine and one molecule of the unusual amino acid phosphinothricin (PT).The bioactive … trulia yuma foothillsWebPhosphinothricin-producing Streptomyces spp. also have an enzyme that detoxifies l -phosphinothricin by acylating it. This enzyme is encoded by the bar gene. Bar is the abbreviation of bialaphos resistance. Bialaphos is a GS-inactive tripeptide produced by the same microbe. It is degraded by plants to form l -phosphinothricin. philippe-thierry douambaWebTraductions en contexte de "Tripeptides" en français-allemand avec Reverso Context : Tripeptides analeptiques, procédé pour leur préparation et leur composition pharmaceutique. philippe thillayWebMolecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736. JAV Blodgett, JK Zhang, WW Metcalf. ASM Antimicrobial Agents and Chemotherapy, 2005. PMID: 15616300; PMC: PMC538901; DOI: 10.1128/AAC.49.1.230-240.2005 in the news: … philippe thill